The principal cytochrome P450 isoenzyme concerned seems to become CYP2E1, with CYP1A2 and CYP3A4 as additional pathways. Close to 85% of an oral dose appears while in the urine inside of 24 several hours of administration, most since the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug.If concomitant use by using a CY